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CCK-8文献索引 (2019-12-11)
CCK-8文献索引
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杂志简称
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1

Chimeric peptidomimetic antibiotics against Gram-negative bacteria,
Nature,2019,doi:10.1038/s41586-019-1665-6

2019
43
Nature
HeLa cell,HepG2 cell
2

PU.1 controls fibroblast polarization and tissue fibrosis,
Nature,2019,566,344–349

2019
43
Nature
Human dermal fibroblasts
3

Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation,
Nature,2016,534,710-713

2016
43
Nature
HeLa cells
4

Transfer of mitochondria from astrocytes to neurons after stroke,
Nature,2016,535,551-555

2016
43
Nature
Neurons
5

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia,
Nature,2015, 521,357–361

2015
43
Nature
Human ALL cells
6

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation,
Nature,2014,511(7507),90-93

2014
43
Nature
FaDu cells
7

Sema3A regulates bone-mass accrual through sensory innervations,
Nature,2013,497(7450),490-493

2013
43
Nature
Osteoblasts
8

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase,
Nature,2011,473(7346),234-238

2011
43
Nature
Endothelial cell
9

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability,
Nature,2011,470(7334),419-423

2011
43
Nature
MEF cell
10

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans,
Nature,2011,477(7362),99-102

2011
43
Nature
A2780 cells
11

Frequent inactivation of A20 in B-cell lymphomas,
Nature,2009,459(7247),712-716

2009
43
Nature
KM-H2 cells
12

Modulation of microRNA processing by p53
Nature,2009,460(7254),529-33

2009
43
Nature
HCT116 cells
13

Oncogenic mutations of ALK kinase in neuroblastoma,
Nature,2008,455(7215),971-4

2008
43
Nature
SK-N-SH cells,LAN-2 cells
14

Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis,
Nature Materials,2019,doi: 10.1038/s41563-019-0462-9

2019
38.8
Nature Materials
HT-29 cells
15

Parenchymal and stromal tissue regeneration of tooth organ by pivotal signals reinstated in decellularized matrix,
Nature Materials,2019,18(6),627-637

2019
38.8
Nature Materials
HUVECs
16

Guiding intracortical brain tumour cells to an extracortical cytotoxic hydrogel using aligned polymeric nanofibres,
Nature Materials,2014,13(3),308-16

2014
38.8
Nature Materials
Human U87MG and Rat RT2 cells
17

A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy,
Cell,2019,178(3),552-566

2019
36
Cell
HeLa cells
18

Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling,
Cell,2019,176(6),1477-1489

2019
36
Cell
HEK293T stable cells
19

Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression,
Cell,2019,177(3),722-736

2019
36
Cell
HepG2 cells
20

B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies,
Cell,2018,173(2),470-484

2018
36
Cell
Leukemia cells
50

Structurally and Functionally Optimized Silk‐Fibroin–Gelatin Scaffold Using 3D Printing to Repair Cartilage Injury In Vitro and In Vivo,
Advanced Materials,2017,29(29),doi: 10.1002/adma.201701089

2017
25.8
Advanced Materials
BMSCs
45

Chirality Controls Mesenchymal Stem Cell Lineage Diversification through Mechanoresponses,
Advanced Materials,2019,doi.org/10.1002/adma.201900582

2019
25.8
Advanced Materials
MSC
23

Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma,
Cell,2012,150(6),1135-1146

2012
36
Cell
HEK293T cells
24

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing,
Cell,2012,150(6),1107-1120

2012
36
Cell
Ba/F3 cells
25

Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease,
Cell,2010,142(6),857-867

2010
36
Cell
Mouse primary neuron
26

Autocrine VEGF Signaling Is Required for Vascular Homeostasis,
Cell,2007,130(4),691-703

2007
36
Cell
Endothelial cells
27

Precise targeting of POLR2A as a therapeutic strategy for human triple negative breast cancer,
Nature Nanotechnology,2019,14 , 388–397

2019
33.4
Nature Nanotechnology
MDA-MB-231,MDA-MB-453
28

Metal nanoparticles in the presence of lipopolysaccharides trigger the onset of metal allergy in mice,
Nature Nanotechnology,2016,11,808–816

2016
33.4
Nature Nanotechnology
Splenocytes
29

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index,
Nature Biotechnology,2019,37640–650

2019
31.8
Nature Biotechnology
HeLa cells
30

Multi-omic measurements of heterogeneity in HeLa cells across laboratories,
Nature Biotechnology,2019,37,314–322

2019
31.8
Nature Biotechnology
HeLa cells
31

Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury,
Nature Medicine,2016,22,1335–1341

2016
30.6
Nature Medicine
Neural stem cells
32

Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity,
Nature Medicine,2016,22(5),547-56

2016
30.6
Nature Medicine
Stem cell
33

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis,
Nature Medicine,2015,21(2),150–158

2015
30.6
Nature Medicine
Fibroblasts
34

Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer,
Nature Medicine, 2013,19, pages329–336

2013
30.6
Nature Medicine
SNU475,SNU449,SNU398,HepG2,HUVEC
35

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition,
Nature Medicine, 2011, 17(7), 875-882

2011
30.6
Nature Medicine
HS578T and HS578Bst cell
36

Mesenchymal stem cell–based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α,
Nature Medicine, 2011,17(12), 1594-1601

2011
30.6
Nature Medicine
BMMSCs
37

Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance,
Nature Medicine, 2010, 16(12), 1414-1420

2010
30.6
Nature Medicine
PC3,LNCaP
38

Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche,
Nature Medicine, 2007, 13(10), 1219-1227

2007
30.6
Nature Medicine
Stem cell
39

A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAF V600E-Mutant Brain Tumor,
Cancer Discovery,2018,8(9),1130-1141

2018
26.3
Cancer Discovery
BRAFV600E cells
40

Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma,
Cancer Discovery,2017,7(6),630-651

2017
26.3
Cancer Discovery
AGS,GES1,SNU1967 cells
68

Transcriptional Regulation of the Warburg Effect in Cancer by SIX1,
Cancer Cell,2018,33(3),368-385

2018
23.9
Cancer Cell
ZR75-1 cells
76

Lower Circulating Folate Induced by a Fidgetin Intronic Variant Is Associated With Reduced Congenital Heart Disease Susceptibility,
Circulation,2017,135(18),1733-1748

2017
23
Circulation
HEK293T
43

Biomimetic Metal–Organic Framework Nanoparticles for Cooperative Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy,
Advanced Materials,2019,31(15),1808200

2019
25.8
Advanced Materials
4T1 cells
46

Engineering Biomimetic Platesomes for pH-Responsive Drug Delivery and Enhanced Antitumor Activity,
Advanced Materials,2019,31(32),e1900795

2019
25.8
Advanced Materials
CT26, 4T1, and Pan02 cells
54

Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma,
Nature Genetics,2018,50,338–343

2018
25.4
Nature Genetics
ESCC cell
41

A Highly Efficient Tumor-Targeting Nanoprobe with a Novel Cell Membrane Permeability Mechanism,
Advanced Materials,2019,31(12),e1807456

2019
25.8
Advanced Materials
4T1 cells
21

Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy,
Cell,2017,170(3),548-563

2017
36
Cell
HCT116; HT29
48

Securing the Payload, Finding the Cell, and Avoiding the Endosome: Peptide-Targeted, Fusogenic Porous Silicon Nanoparticles for Delivery of siRNA,
Advanced Materials,2019,31(35),e1902952

2019
25.8
Advanced Materials
CAOV-3,J774a.1 cells
49

Semiconducting Polymer Nanoparticles for Centimeters‐Deep Photoacoustic Imaging in the Second Near‐Infrared Window,
Advanced Materials,2017,29(41),1703403

2017
25.8
Advanced Materials
Mia PaCa-2, A549 and HeLa cells
63

Exome sequencing of hepatitis B virus–associated hepatocellular carcinoma,
Nature Genetics, 2012, 44(10), 1117-1121

2012
25.4
Nature Genetics
HCC cell
69

Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential,
Cancer Cell,2016,30(5),779-791

2016
23.9
Cancer Cell
AML Cells
52

Poly(methacrylic acid)-grafted carbon nanotube scaffolds enhance differentiation of hESCs into neuronal cells,
Advanced Materials,2010,22(32),3542-7

2010
25.8
Advanced Materials
Embryoid bodies
53

Transposable elements drive widespread expression of oncogenes in human cancers,
Nature Genetics,2019,51,611–617

2019
25.4
Nature Genetics
H1299 cell
80

A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer,
Cell Metabolism,2019,30(6),1107-1119

2019
22.4
Cell Metabolism
NSCLC cells
81

IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties,
Cell Metabolism,2019,29(6),1363-1375

2019
22.4
Cell Metabolism
Splenocytes
56

Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer,
Nature Genetics,2016,48, 500–509

2016
25.4
Nature Genetics
HCC cell
57

A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma,
Nature Genetics,2014,46, 371–375

2014
25.4
Nature Genetics
Jurkat, SUP-T1 and MOLT-4 cells
58

Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas,
Nature Genetics,2014,46,726–730

2014
25.4
Nature Genetics
HCT116
59

Somatic RHOA mutation in angioimmunoblastic T cell lymphoma,
Nature Genetics,2014,46,171–175

2014
25.4
Nature Genetics
Jurkat cells
44

CD44‐Specific A6 Short Peptide Boosts Targetability and Anticancer Efficacy of Polymersomal Epirubicin to Orthotopic Human Multiple Myeloma,
Advanced Materials,2019,doi.org/10.1002/adma.201904742

2019
25.8
Advanced Materials
LP-1 cells d
61

Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms,
Nature Genetics,2014,45,1232–1237

2013
25.4
Nature Genetics
MOLM-13 cells
62

Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese,
Nature Genetics, 2012, 44(4), 426-429

2012
25.4
Nature Genetics
Prostate cells
89

Increased levels of the long intergenic non-protein coding RNA POU3F3 promote DNA methylation in esophageal squamous cell carcinoma cells,
Gastroenterology,2014,146(7),1714-26.e5

2014
19.2
Gastroenterology
Eca-109-control, Eca-109-linc-POU3F3
64

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression,
Nature Genetics, 2012, 44(11), 1199-1206

2012
25.4
Nature Genetics
Kelly cells
65

Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis,
Nature Genetics,33,172-176

2003
25.4
Nature Genetics
ES cells
74

The tumor suppressor PTEN has a critical role in antiviral innate immunity,
Nature Immunology,2016,17,241–249

2016
23.5
Nature Immunology
PC-3 cells
67

Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer,
Cancer Cell,2018,33(1),137-150

2018
23.9
Cancer Cell
TMK1 cell
47

Highly Efficient and Environmentally Friendly Fabrication of Robust, Programmable, and Biocompatible Anisotropic, All-Cellulose, Wrinkle-Patterned Hydrogels for Cell Alignment,
Advanced Materials,2019,31(46),e1904762

2019
25.8
Advanced Materials
MC3T3-E1 cell
22

Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity,
Cell,2017,170(3),492-506

2017
36
Cell
HCC cell lines
70

Targeting Transcriptional Addictions In Small Cell Lung Cancer With a Covalent CDK7 Inhibitor,
Cancer Cell,2014,26(6),909-922

2014
23.9
Cancer Cell
mSCLC cell
71

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming,
Cancer Cell, 2012, 22(1), 66-79

2012
23.9
Cancer Cell
MEFs
72

Polycomb-Mediated Loss of miR-31 Activates NIK-Dependent NF-kB Pathway in Adult T Cell Leukemia and Other Cancers,
Cancer Cell, 2012, 21(1), 121-135

2012
23.9
Cancer Cell
TL-Om1 cells
73

E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer,
Cancer Cell, 2008, 13, 272-286

2008
23.9
Cancer Cell
Snu-16 cells
42

A Self-Pumping Dressing for Draining Excessive Biofluid around Wounds,
Advanced Materials,2019,31(5),e1804187

2019
25.8
Advanced Materials
HDF-a cell
75

Functional Metabolomics Characterizes a Key Role for N-Acetylneuraminic Acid in Coronary Artery Diseases,
Circulation,2018,137(13),1374-1390

2018
23
Circulation
Neonatal Rat Ventricular Myocytes
60

Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma,
Nature Genetics, 2013, 45(6), 632-638

2013
25.4
Nature Genetics
ESCC cell
77

Magnetic Resonance Imaging Overestimates Ferumoxide-Labeled Stem Cell Survival After Transplantation in the Heart,
Circulation,2008,117(12),1555-62

2008
23
Circulation
Cardiac-derived Stem cells
78

Magnetic Resonance Imaging Overestimates Ferumoxide-Labeled Stem Cell Survival After Transplantation in the Heart,
Circulation,2008,117(12),1555-62

2008
23
Circulation
Cardiac-derived Stem cells
79

Pioglitazone Prevents Acute and Chronic Cardiac Allograft Rejection,
Circulation,2006,113(22),2613-22

2006
23
Circulation
T-cell
55

Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation,
Nature Genetics,2016,48,747–757

2016
25.4
Nature Genetics
Pancreatic Ductal Adenocarcinoma
88

Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That Regulate Metastasis,
Gastroenterology,2017,152(8),1985-1997.e12

2017
19.2
Gastroenterology
ESCC cell
82

Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition,
Cell Metabolism,2014,20(1),133-44

2014
22.4
Cell Metabolism
HCCcells
83

Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons,
Cell Stem Cell,2019,25(4),514-530

2019
21.4
Cell Stem Cell
Neurons
84

PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy,
Cell Stem Cell,2018,23(5),700-713

2018
21.4
Cell Stem Cell
MOLM13, OCI-AML2, and OCI-AML3
85

Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells,
Cell Stem Cell,2017,20(3),303-314

2017
21.4
Cell Stem Cell
OVCAR5, COV362
86

Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells,
Gastroenterology,2018,154(5),1465–1479.e13

2018
19.2
Gastroenterology
Hepatic Stellate cells
87

Small Nucleolar Noncoding RNA SNORA23, Up-Regulated in Human Pancreatic Ductal Adenocarcinoma, Regulates Expression of Spectrin Repeat-Containing Nuclear Envelope 2 to Promote Growth and Metastasis of Xenograft Tumors in Mice,
Gastroenterology,2017,153(1),292-306.e2

2017
19.2
Gastroenterology
PDAC cell
51

DNA‐Nanostructure–Gold‐Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy,
Advanced Materials,2016,28(45):10000-10007

2016
25.8
Advanced Materials
4T1-fLuc cells
66

Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation,
Cancer Cell,2019,35(2),191-203

2019
23.9
Cancer Cell
HepG2 ,MCF 7,SMMC7721,HCT116,SK-Hep1,BEL7404,A549,HeLa,CaskI,RKO,L74T
90

Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells,
Gastroenterology,2010,139(3),918-28

2010
19.2
Gastroenterology
HCT116, HT29, LOVO, LS174T, RKO, and SW480
91

Inhibitor of κB Kinase Beta Regulates Gastric Carcinogenesis via Interleukin-1α Expression,
Gastroenterology,2010,139(1),226-38.e6

2010
19.2
Gastroenterology
AGS and SH101
92

Deficiency of GMDS Leads to Escape from NK Cell-Mediated Tumor Surveillance Through Modulation of TRAIL Signaling,
Gastroenterology,2009,137(1),188-98, 198.e1-2

2009
19.2
Gastroenterology
NK cells
93

Heat Shock Protein 70 Inhibits Apoptosis in Cancer Cells Through Simultaneous and Independent Mechanisms,
Gastroenterology,2009,136(5),1772-82

2009
19.2
Gastroenterology
Pancreatic cancer cells
94

Deletion of Apoptosis Signal-Regulating Kinase 1 Attenuates Acetaminophen-Induced Liver Injury by Inhibiting c-Jun N-Terminal Kinase Activation,
Gastroenterology,2008,135(4),1311-21

2008
19.2
Gastroenterology
Hepatocytes
95

REG Iα protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer,
Gastroenterology,2005,128(3),642-53

2005
19.2
Gastroenterology
AGS cells
96

Regulation of hepatic stellate cell activation and growth by transcription factor myocyte enhancer factor 2,
Gastroenterology,2004,127(4),1174-88

2004
19.2
Gastroenterology
HSCs