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近期《自然》及其子刊文献中CCK-8的应用 (2013-7-23)
         随着生物科研水平的日益提升,相关技术领域的实验方法也面临着新一代的革新。同仁化学研究所的细胞活力检测试剂盒——Cell Counting Kit-8由于其卓越的灵敏度与准确性,以及高重现性与简便操作等特性,自被国内外广大高校、科研院所的硕士、博士、博士后等青年学者和科技公司的科研人员所用于生命科学和相关交叉学科后,大量与之相关的高质量学术性文献被国内外知名杂志认可并刊登。近日,同仁化学研究所工作人员将近年来以CCK-8法用于细胞增殖、毒性检测,并刊登于英国权威科学杂志《自然》及其子刊的相关文献做了整理,供奋斗在生物领域前沿的科研人员做参考。
No. 文献名 杂志名与页数 实验细胞 IF
1 Sema3A regulates bone-mass accrual through sensory innervations Nature,2013,497,490-493 osteoblast cells 38.5
2 Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase Nature,2011,473,234-238 Endothelial cell 38.5
3 Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability Nature,2011,470,419-423 MEF 38.5
4 Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma Nature Genetics,2013,45(6), 632-638 YES2 and KYSE-450 cells 35.2
5 Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese Nature Genetics,2012, 44(4),426-429 Prostate cell 35.2
6 Exome sequencing of hepatitis B virus–associated hepatocellular carcinoma Nature Genetics,2012, 44(10),1117-1121 HCC cell lines 35.2
7 Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer Nature medicine,2013,19(3),329-336
HepG2 cells,HUVEC,
Lox IMVI cells
22.8
8 Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition Nature medicine,2011,17(7),875-882 HS578T and HS578TBst cells 22.8
9 Mesenchymal stem cell–based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α Nature medicine,2011,17(12),1594-1601 BMMSCs 22.8
10 Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance Nature Medicine,2010,16(12),1414-1420 LNCaP-FGC, MDA-PCa-2b and PC-3 cells 22.8
11 ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death Nature Cell Biology,2013,15(5),481-490 HEK293 cells 20.7
12 Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA Nature Cell Biology,2010, 12(4),390-408 SMMC-7721 cells 20.7